"I have a client with severely dehydrated cheeks but lots of comedones on the T-Zone. I am treating her with facials but do you think she should use 2 different moisturizers to help combat the oiliness and dehydration? It only recently started happening."
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Exfoliate the whole face to remove the dry skin on the cheeks and the impaction plugs in the T-Zone. It is ok to use two different moisturizers on the skin; you'll want a more emollient moisturizer for the cheeks and maybe try an oil controlling lotion for the T-Zone if needed. Otherwise, try an oil free, lightweight moisturizer and an overnight, decongesting gel.

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