News

  • Getting the Most out of Vitamins

    In the past decade, scientific studies have supported the use of topically applied vitamins in skin care products. At The International Dermal Institute, we have been researching how we can optimize the delivery of these actives into the skin. Knowing that liposomes, liquid filled bubbles made from layered phospholipids, could be filled with vitamins and used as a delivery vehicle, we wanted to see if we could maximize the use of this technology. Our research revealed that while liposomes provide enhanced delivery of actives into the skin, they do have a few limitations- one of which is the amount of vitamins that can be loaded inside.

    So you can imagine how excited we were when we found a more advanced liposomal structure that is the result of high pressure homogenization; this new, smaller type of structure enables a higher amount of actives to be loaded into the bubble and represents the next generation in liposome technology. When liposomes come in contact with our skin, the phospholipids, being very similar to the skin’s natural membrane lipids, allow the liposome to fuse with our skin’s membrane, delivering its contents. In the case of these newer liposomes, more actives can be delivered. We have found that they work very well with Retinyl Palmitate, (a derivative of Vitamin A), Tocopheryl Acetate (Vitamin E) and Magnesium Ascorbyl Phosphate (a stable derivative of vitamin C).

    When comparing these encapsulated vitamins vs. their non-encapsulated counterparts, studies have shown higher effectiveness with the encapsulated forms. For example, studies comparing collagen stimulation when an empty liposome is used, vs. free Magnesium Ascorbyl Phosphate (MAP) and encapsulated MAP, show that MAP stimulates collagen almost three times more than empty liposomes; however, encapsulated MAP was over 25 times more effective than the empty liposome.

    This advanced form of technology enables cosmetic chemists to maximize the amount of actives delivered to the targeted site to optimize skin health. Look for more of these new advances over the coming years!

    Leave a Comment

    Terms in bold are required.

    (will not be published)